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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bf0335c9a2a220f14e1fa383b40e1311b89cdfb250743642007f80184ed1cfc' 
  AND token = 'zkJt+uamrXfwNipGDFcHI2sEORxvmMEeoTswhyf9Yhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}