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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e8c557dcc378db159fc5a65ad93aa2c3465caa8edb20b9bbcd96fdd36a2e15d' 
  AND token = '2wS5j9kVjDxJUrks4P6PaDkeW5VqCT+V8bM7XbWdwJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}