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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d9879000287fe38da9615461d7db44c4f9cb9f27c2d9b49f2446ac12240a750' 
  AND token = '3ZGceWV8Xc/pMI+My2nq7SYCXSIGHg0gJC+I9+sS5uI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}