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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b72ff53770eac6ae87c5b827398894aafc14de0c0b6b9019f6ac45964a7c8456' 
  AND token = 'QgJPvg5fITs2hiZUk1oOeeY+MOHkk5vznqosDcMTYFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}