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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9aa2fcefaeb5cfe5e0120ef32b8968ee55056005bd118de2559a79068942b823' 
  AND token = 'os1oxxFwaVBiHY8SJD/3SpaLVz6Xju54++izvkie7cg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}