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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8401e20d7f09477cb0e0960200f537b6f99b077a30e3dcfb7bf0e37b74dc7358' 
  AND token = '3acSFditvtmAsxWmaoUKBnDOgtzRPFjpip3tqpNkLII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}