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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a2d4afe0d8119388bf6467bd17ac69838bb1654f49c083e2f27008a8c1260dd' 
  AND token = '54rLs++NqrAT0BZM1MZz6Y1suaIboSfsbEXPJbBrytA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}