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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42b7d3191ed53ef065027cbbf62683bc4c4119fbb9f2bff7b7babc9b46836a65' 
  AND token = 'H1tI+QO+GG+W3ELQXXicmMy/RBpuGNuO1WjV1OVeLmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}