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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1ca7ded55c3dc68704fbcce9490319f1b48e4b9b757dab8ed80b51c544cb6be' 
  AND token = 'yeBCyH/mNGciErJjSiwN58CTmb/8lPiGbN93ZrO/gtQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}