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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '604cf5bd462659859d3fba72bf29204f07d9df85de83c805559b606eae600c25' 
  AND token = 'QdudQCTX7hpOyyW5lGIdeMlm+2TC+Rstgg/ufR4RxRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}