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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49a1ae93f2a1ccec95993387f66c3b719e3c181ac9938b295ab71c8297af9d1c' 
  AND token = '3UxyeAIZY+E54WfHc6N/aeHjb6yyTGPIV0QAlsySuzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}