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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e0bed558c7fb62c66ffc45d0c33017922d10da65243161ea74c5cbbf3742d07' 
  AND token = 'U13CYPFFYsq5ExawuIL0D2LuUsG3cwyMyH8gJ8OSpP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}