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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ddf880c555efe9a54b84b970ccff2f048e74dd2b576eac378afdf6a0dfda459' 
  AND token = 'lIexA6/fvcznmF3hQF8kBsk28gcy23sHjQbEbQByt94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}