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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b5ccb164842ee5bb645300da93c770a830241fb51bb0f5c1043d2a4c949136b' 
  AND token = '2KHrDjZN0a5ejQOiNO0/0HKBH8Qvsup2W/gnCi72vmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}