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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '995d38baa5dfebb2f28e0405333367d741fc15a0885a2b165383da4a9602598d' 
  AND token = 'J6VJMzo/rLA2P+mn/ItZojR02sK+jeVxD02Ti9wnrTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}