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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dc4f8af456306d88a10d634a0adf9764a591c4c6d77a20c2e02b4cf48507f3d' 
  AND token = 'TvuU+vJXrKSC9Rxlh9MZIeEOyLu26rZOkF+48GW1Y5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}