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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e53b97d3289ebd54b6964293b6a832505f5f1913633d7294a4a5361c5ee1a4c' 
  AND token = 'FmSKtm/dUOd2xy+sZdnmjJsqkUg6p0UPqXd+XvmyKbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}