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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd79c5a055d7a989c25e43d767dc5ece500a850d65fbe2c657ee79ca185e0f39c' 
  AND token = 'Rero3+0LRc+XnUI7GzzzfvUnWoB+6weJx+K5EeDOuuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}