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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd58e313d836ca5bc61466f19a0b8c9f25c314eecd84f138d92cdcf6c7fa3825' 
  AND token = '0NL9iEYE3xrvN4BFFXUMVOJopSDqrqbNZuWl46B1NI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}