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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e54bcf21640097a64075779ae8883d0f42be7759a60e5e60c49f07495ffb7804' 
  AND token = 'jFV5JygXhfDfdjlsXjkFOKP1FUrK92TAGVTt5tjfig4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}