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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ae69a78e7dec4fe6d0c0534446066adda088633a9a6602a97e6e691384ceaa0' 
  AND token = 'geyxp+bvDEJ9T06brabT5Y9Dlsw/zXc1eOryU9VH8Kk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}