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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87273b6019b5e6753abd51e978d044223901be9c331b29b6d3086d88aa586d9a' 
  AND token = 'QJQJaJp2gZ+iPd5ODZa5H8AMmqN6FxsEnZsvY0nGsqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}