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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '143b388992a32084b1dcffe1d3e1051a35295ed4b8287276c59e5d7b76cf99eb' 
  AND token = 'OiYjfwQsyns5I2A/91AHZcQ7qEN23+MOJadDIwoxLA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}