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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bd6094263125ab087cb3a1b9faf365db84256a0751ad3ab36defbf7ac494e2f' 
  AND token = 'cQdMyoeM+zclpXedTyt3Nmc1cl3WYmwJQxRs6wCu8Do=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}