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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f495b5855d1b790dfd57fda3eaf81f7d7d5806a187a10c8ec750e10e30a451b4' 
  AND token = 't6dDa99fteW7t3W+ofxRGzMRBZZRDZaM/9D8i5KT7y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}