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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7718ac992eef314b7e1328b4532ecd36a1cc9220b0522947da60e2e47523c1a1' 
  AND token = 'eBZUrvYXSFVZdOsHdd0o2U3p5P5hDTo3SFAkN2JnfJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}