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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a70dd59700a28a9ddc57fe05dc72a31b3065ddd2d9dca79834120d966955a27' 
  AND token = 'uUZ3wC2ylozhEc6dvPHoBBr+KvsCD6yRp4BDQ7xDZaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}