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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa525835418af2d3cf1b3b67314ac14ee19d28cce67a5effbe49e5b86476e3cc' 
  AND token = 'bH7D+B6bjbkRsvAAcpQsFkN2HlZfBdAc8vo/cjgKVAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}