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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4599834e9b382edc5e8177644ce10f1d19b72549df485168b782c96c4f9fa37' 
  AND token = 'HJ2G7VaNk5NaG1j8bvpkzP7YHo1M6R0xAHvhguewl7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}