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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2d6add857f887e86d710c3307bf37f8eec723c33defd6e7f05d412659119fb8' 
  AND token = 'iVHZES2zL3zMEoTU19RbrRk3+rlVQZEbGsM2wEH1NqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}