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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e51fe9064ca6117cca5fd70790c40cccc6917b0a2fcf67d19fbe1da02c2f015e' 
  AND token = 'dk33wCtV+Qk1FP0+7Rv9iULSWnMC0Q2joei0ZMHgcZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}