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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '387c65e3239fbb8a7d4b25af1c5c0e9683c1f44ca968dfb368fda2edc46f1ba2' 
  AND token = '1+vEFcSXzp/lGqgv1888bv5iw4YTfQPBs0krFAfrQlk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}