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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1603befe0807c9f3e9f926f76966dab99a6273c615ed2bd505108ee1a73ee24' 
  AND token = 'QeT0OAOc8kqQqabMMN6SkR1mVCaS3r5khulrRRNpFuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}