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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f50038b06460111ffb3e9a145f4f76c08a3ae1509f24fd25984cdd015a0d6e0' 
  AND token = 'kdZfs1nQ4GZxADQLSBNS4fZed3diTs3j57n1EKbp14U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}