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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ba87a0a1c8564f428601bc1408fbdcf0a2f5011eac590f913f5e5afe3ea53e80' 
  AND token = 'jfIOODxAb8z+4RaTJU9iWAepajm19PQVgg4tG2HZBwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}