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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1102c215ff2e7965a9348a511c2aa2ea0e3a6a58dd596ba2e37424ee4555602f' 
  AND token = '+tN+KGlQmbxMRXbbcrP4dKtAB2zG7hAdPAxP6hODzKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}