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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cf35d78c30d48b440c8d471ac91f5766a5b32190b6e7c050405a5739abb0c80' 
  AND token = '3XkGn2Qp1Bje3skxMmWmsEOjtmAara80/vy6cKcECm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}