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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6445b54749ccf25a3545aaf8bc1415057cfbc2874890c18996a9762f51dc0c5' 
  AND token = '0AmdwyAFoabqeDTNnMPE5BmcfjQrF5lnpHaaaIhy8oE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}