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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f7fde3943eb49c9c068eeb6a9afeedd05aaac777ae1518794675d453843b40e' 
  AND token = 'ei4zttPPN7AV1NUzKbsRcoCNlIyPUapm72at8+fY4Hk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}