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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0257455f126ba8d1ad2a7b1202d87812698299078c4e0d0f73e5f7000ab75a7' 
  AND token = 'sbc6uTa31caA/3GwK3mlPFXGjCpAtkZ1xW97S6mMk6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}