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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3454aec279cd3cdeba2dda458022c114f6eb9bea31e986272c1695d196eb4634' 
  AND token = 'D/D0/TXCsutm2JiiS4re64SBUjBEqo93fTBzq5kFDLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}