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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e4e5f71b0b3c50bf1cec41a71c9565276d1de07ed2f85450beeee40c15accb1' 
  AND token = 'VGcCE3+e1UhQbuWFKy5Ii+DsKnuRWKep15A/1l+enYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}