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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6456ab9cf7e12706163a387e97f0e02bacf7d7009d02ad276a062a30d36ab140' 
  AND token = 'Vwl95F/gbee9agaDOUOofnm+8mU0LRPU5jfydq8OOuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}