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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39b8dca69dfde11fe01246f1f16ec8f6f0c22df185af14d22fa4e9f0e463dfea' 
  AND token = 'CeAkRBtnLWMuSpU9012BVW/donwpZ9ntwNqrcZNcIk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}