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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '825e45a3d3f61f8c6693851b20bee009a5137a704db8c5a5a52edd4e975a1388' 
  AND token = 'kx4dI8rljz14cuVAAxZllyljPNUTWREW1eVvZjEZiao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}