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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4f8a7248009017c22081f3acc465ea87b5da0d02432ec6e6329d4f5e92e041c' 
  AND token = 'Rg4pALE6MNpa/vk0vnc35LiUqRmHtNnHsfUvF64fSEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}