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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54fd3f3c2d1e1a166f690104d5630faaeb5e7f148cd4e453f7312afe647c46f1' 
  AND token = 'RzQO32t8Zv4thyzfeCz45AOVerJj0pRH0xz6ClDPcek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}