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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1e43fd23ff7c475aec6ef783b78c9582e4d35cfb46319d8d4d42e644913c97e' 
  AND token = 'bS0hO/FnfYXOt9lClLBQXeOvcS0hjogRt8Cm/VcgeAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}