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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64d532404acca43e492405f62b715963a6db5d1c5b83143f8f8faa0724a70a52' 
  AND token = 'T54zJ5ptNxVcvPikUij3uO6y3hSLSPJHiWTC6dqnHY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}