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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '258a7fd97efa7bb2a0c294df5bccf6edd46065bc2ad1b2a2287e85f8a6052371' 
  AND token = 'EI0UQ4ne2ReqrhRlFVTahKnstbmncG10CQd136Iln6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}